Scientific studies on osteoporosis screening using Bonescreen (selection):

  1. Automated Opportunistic Osteoporosis Screening in Routine Computed Tomography of the Spine: Comparison With Dedicated Quantitative CT. Sollmann N et al. J Bone Miner Res. 2022 May 22. doi: 10.1002/jbmr.4575.
    This paper shows that Bonescreen’s technique is on par with dedicated QCT measurements.

  2. Proposed diagnostic volumetric bone mineral density thresholds for osteoporosis and osteopenia at the cervicothoracic spine in correlation to the lumbar spine. Rühling Set al. Eur Radiol. 2022 Apr 6. doi: 10.1007/s00330-022-08721-7.
    This paper introduces reference values for bone mineral density measurements for different parts of the spine.

  3. Level-Specific Volumetric BMD Threshold Values for the Prediction of Incident Vertebral Fractures Using Opportunistic QCT: A Case-Control Study. Dieckmeyer M et al. Front Endocrinol (Lausanne). 2022 May 20;13:882163. doi: 10.3389/fendo.2022.882163.
    This paper reports diagnostic accuracy for different parts of the spine.

  4. Automated detection of the contrast phase in MDCT by an artificial neural network improves the accuracy of opportunistic bone mineral density measurements. Rühling S et al. Eur Radiol. 2022 Mar;32(3):1465-1474. doi: 10.1007/s00330-021-08284-z.
    This paper introduces an automated correction for density measurements in contrast-enhanced scans.

  5. Automatic opportunistic osteoporosis screening in routine CT: improved prediction of patients with prevalent vertebral fractures compared to DXA. Löffler MT et al. Eur Radiol. 2021 Aug;31(8):6069-6077. doi: 10.1007/s00330-020-07655-2.
    This paper reports the diagnostic performance of Bonescreen and shows superiority compared to the current state-of-the-art method DXA.

  6. Opportunistic Osteoporosis Screening Reveals Low Bone Density in Patients With Screw Loosening After Lumbar Semi-Rigid Instrumentation: A Case-Control Study. Löffler MT et al. Front Endocrinol (Lausanne). 2021 Jan 11;11:552719. doi: 10.3389/fendo.2020.552719
    This paper shows that Bonescreen may be valuable for surgical planning to prevent later complications.

  7. Opportunistic QCT Bone Mineral Density Measurements Predicting Osteoporotic Fractures: A Use Case in a Prospective Clinical Cohort. Leonhardt Y et al. Front Endocrinol (Lausanne). 2020 Nov 9;11:586352. doi: 10.3389/fendo.2020.586352.
    This paper shows the utility of opportunistic measurements for a fracture liaison service.

    Please find more publications related to the topic on Pubmed: